Pain

• Pain in the leg is the most common symptom of bone cancer. It will gradually build and become a constant pain. It is generally worse at night or when the leg is being used. Over time, it may cause a limp.
  
  

Swelling

• Swelling in the leg may occur after a few weeks. A lump or mass in the leg may also be present.
  
  

Fracture

• Most of the time, bones in which cancer develops do not break, although the cancer does weaken the bone. When a bone fractures, it is usually described as a sudden severe pain in the limb that had been sore for a few months.
  
  

Weight Loss and Fatigue

• Weight loss and fatigue may be experienced in conjunction with bone cancer.
  
  

Other Organs

• When the cancer spreads to other organs, additional symptoms may occur. For example, if the cancer spreads to the lungs, difficulty breathing may be experienced.