Oral toenail fungus cure or medications have received more than enough bad publicity from the internet as any drugs would have saying their bad effects are more than what any patient will bargain their nails with.
But has anyone ever bothered to give the oral toenail fungus cure the justice of giving the full account of how they work.
After all, these are also remedies for the real enemy, the fungal infection.
There are three types of oral toenail fungus cure out and made available upon prescription; allylamines, azoles and griseofulvin.

• Allylamines - are unsaturated amines, organic chemical with nitrogen, the antifungal allylamine is called Terbinafine hydrochloride.
  This drug dissolves in fat or lipid and stored in lipids found in the skin, nails and other fatty tissues.
  From there the toenail fungus remedy works by preventing production of sterol, an equivalent of cholesterol in the human body, in plants including fungi, this is a main component of the cell membrane which protects the inside of a cell from the outside environment.
  Its side effects include liver damage, and can also worsen the disorder Subacute cutaneous lupus erythematosus - a lupus condition common in women ages 15 to 40 years old, indicated with skin lesions or cuts that are scaly, which can evolve into the appearance of psoriasis plaque.
  
• Azoles - just like allylamines it works by preventing or inhibiting the production of sterol that is needed for the foundation of cell membrane called cytoplasmic membrane.
  Although liver damage is still seen as a bad effect, but only in rare cases.
  Though the main concern in this type of oral toenail fungus remedy is irregular heart rate or heart beat.
  It affects the QT intervals or affects the electrical cycle of the heart, prolonged intervals in the cycle means irregularity in heart rate.
  One severe but very rare effect is the Steven-Johnson syndrome - death of skin cells; that results in separation of the epidermis to the dermis.
  
• Griseofulvin - is different in how it works from the two former types of drugs, it attaches or binds with tubulin protein and slows down or hinder the microtubule function which in turn prevents mytosis or duplication, division of cell into two identical or similar ones.
  Effects adverse to the body are hives, itching, loss of taste sensation, decreased in efficiency of oral contraceptives and even cause conjoined twins.
  

One reason that we should take note of why there is no oral toenail fungus remedy without the bad effects to the body is that fungi and humans share a common molecular characteristic, both have complex cell structure inside the membrane.
So finding a chemical that can kill molecules of fungus without damaging ours is difficult work.
Maybe this is one reason why we should stick in finding a natural toenail fungus remedy that will cure us instead.