Cancer Prevention Overview (PDQ®): Prevention - Patient Information [NCI]-Risk Factors
Some risk factors for cancer can be avoided, but many cannot. For example, both smoking and inheriting certain genes are risk factors for some types of cancer, but only smoking can be avoided. Risk factors that a person can control are called modifiable risk factors.
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General Information About Renal Cell Cancer
Incidence and MortalityEstimated new cases and deaths from renal cell (kidney and renal pelvis) cancer in the United States in 2014:[1] New cases: 63,920. Deaths: 13,860. Follow-up and SurvivorshipRenal cell cancer, also called renal adenocarcinoma, or hypernephroma, can often be cured if it is diagnosed and treated when still localized to the kidney and to the immediately surrounding tissue. The probability of cure is directly related to the stage or degree of tumor dissemination...
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Many other factors in our environment, diet, and lifestyle may cause or prevent cancer. This summary reviews only the major cancer risk factors and protective factors that can be controlled or changed to reduce the risk of cancer. Risk factors that are not described in the summary include certain sexual behaviors, the use of estrogen, and being exposed to certain substances at work or to certain chemicals.
Factors That are Known to Increase the Risk of Cancer
Cigarette Smoking and Tobacco Use
Tobacco use is strongly linked to an increased risk for many kinds of cancer. Smoking cigarettes is the leading cause of the following types of cancer:
- Acute myelogenous leukemia (AML).
- Bladder cancer.
- Esophageal cancer.
- Kidney cancer.
- Lung cancer.
- Oral cavity cancer.
- Pancreatic cancer.
- Stomach cancer.
Not smoking or quitting smoking lowers the risk of getting cancer and dying from cancer. Scientists believe that cigarette smoking causes about 30% of all cancer deaths in the United States.
See the following PDQ summaries for more information:
- Lung Cancer Prevention
- Cigarette Smoking: Health Risks and How to Quit
Infections
Certain viruses and bacteria are able to cause cancer. Viruses and other infection -causing agents cause more cases of cancer in the developing world (about 1 in 4 cases of cancer) than in developed nations (less than 1 in 10 cases of cancer). Examples of cancer-causing viruses and bacteria include:
- Human papillomavirus (HPV) increases the risk for cancers of the cervix, penis, vagina, anus, and oropharynx.
- Hepatitis B and hepatitis C viruses increase the risk for liver cancer.
- Epstein-Barr virus increases the risk for Burkitt lymphoma.
- Helicobacter pylori increases the risk for gastric cancer.