Fecal Calprotectin in the Evaluation of Abdominal Discomfort
Fecal Calprotectin in the Evaluation of Abdominal Discomfort
In conclusion, our study showed that fecal calprotectin values are elevated in patients with organic gastrointestinal disease. We confirmed results of previous studies showing excellent ability of fecal calprotectin to identify mucosal lesions in the colon. Additionally, we expanded the role of fecal calprotectin as a diagnostic test to the upper intestinal tract by demonstrating its ability to identify esophageal and gastric mucosal lesions. Further prospective studies directly comparing recommended guidelines of appropriateness for endoscopy with fecal calprotectin measurements are warranted to establish the value of a biomarker-guided assessment of patients with abdominal discomfort and to explore the cost-effectiveness of such an approach.
Conclusion
In conclusion, our study showed that fecal calprotectin values are elevated in patients with organic gastrointestinal disease. We confirmed results of previous studies showing excellent ability of fecal calprotectin to identify mucosal lesions in the colon. Additionally, we expanded the role of fecal calprotectin as a diagnostic test to the upper intestinal tract by demonstrating its ability to identify esophageal and gastric mucosal lesions. Further prospective studies directly comparing recommended guidelines of appropriateness for endoscopy with fecal calprotectin measurements are warranted to establish the value of a biomarker-guided assessment of patients with abdominal discomfort and to explore the cost-effectiveness of such an approach.