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What Is Mixed Bipolar Disorder?

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What Is Mixed Bipolar Disorder?
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What Are the Treatments for Mood Episodes With Mixed Features in Bipolar Disorder? continued...


Depakote is an antiseizure medication that also levels out moods in bipolar disorder. It has a more rapid onset of action, and in some studies has been shown to be more effective than lithium for the treatment of manic episodes with mixed features

Some other antiseizure drugs, such as Lamictal and Tegretol, are also effective mood stabilizers.

Antipsychotics

Many atypical antipsychotic drugs are effective FDA-approved treatments for manic episodes with mixed features. These include aripiprazole (Abilify), asenapine (Saphris), olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperdal), and ziprasidone (Geodon). Antipsychotic drugs are also sometimes used alone or in combination with mood stabilizers for preventive treatment.

Electroconvulsive Therapy (ECT)

Despite its frightening reputation, electroconvulsive therapy (ECT) is an effective treatment for any phase of bipolar disorder, including manic episodes with mixed features. ECT can be helpful if medication fails or can't be used.

Treatment for Depression in Mixed Bipolar Disorder

Common antidepressants such as Prozac, Zoloft, and Paxil have been shown to worsen mania symptoms without necessarily improving depressive symptoms when depressive and manic symptoms occur together. Most experts therefore advise against using antidepressants during episodes with mixed features. Mood stabilizers (particularly Depakote), as well as atypical antipsychotic drugs, are considered the first-line treatments for mood episodes with mixed features.

Bipolar disorder usually  involves recurrences of mixed, manic, or depressed phases of illness. Therefore, it is usually recommended that medications be continued in an ongoing fashion after an acute episode resolves in order to prevent relapses.

 
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