What Causes RLS (Restless Leg Syndrome)?
Research to determine the causes of Restless Leg Syndrome is ongoing, but so far this has not truly pinpointed a mechanism that is a direct trigger behind this disease.
In other words, RLS has no identifiable origin, that say, for example, influenza does.
It could be that RLS is a final common pathway for multiple causes and mechanisms.
Or it could be that victims have an underlying vulnerability that develops in the presence of one or more pre-existing factors.
The word cause can be used here in a loose fashion to mean something that seems to cause or trigger the disagreeable RLS Symptoms.
In almost half of all cases, RLS is tied to a family trait, but it could certainly have an unknown cause, or be related to another condition.
Primary RLS Primary RLS vary often will include a positive family history.
Between one third and one half of the cases of RLS are transmitted in a pattern that is consistent with dominant traits.
There is also some evidence of a recessive inheritance, which means that RLS cases can be transmitted by the less dominant, or processes, gene.
Primary RLS can also show a dopaminergic deficiency, which could result from a malfunction in the brain stem.
Secondary RLS Some teachers of secondary RLS are referred to as risk factors for RLS, or disorders that occur in conjunction with RLS.
Some examples include periodic limb movements (or PLM), early-onset Parkinson's disease, and end-stage renal disease (ESRD).
RLS can be induced by certain drugs, which include all drugs that block the dopamine receptor.
The use of alcohol and caffeine can also trigger Restless Leg Syndrome.
Another trigger could be that of a physical trauma.
There is no formal research that supports this conclusion, but anecdotal evidence is relatively strong.
And people that suffer from this disease often have an operation or accident to the body or brain, which seems to trigger the disease also.
Still others report that RLS worsens after an accident.
Other triggers that are guilty of worsening pre-existing mild RLS include spinal surgery and arthritis of the lumbar region.
In other words, RLS has no identifiable origin, that say, for example, influenza does.
It could be that RLS is a final common pathway for multiple causes and mechanisms.
Or it could be that victims have an underlying vulnerability that develops in the presence of one or more pre-existing factors.
The word cause can be used here in a loose fashion to mean something that seems to cause or trigger the disagreeable RLS Symptoms.
In almost half of all cases, RLS is tied to a family trait, but it could certainly have an unknown cause, or be related to another condition.
Primary RLS Primary RLS vary often will include a positive family history.
Between one third and one half of the cases of RLS are transmitted in a pattern that is consistent with dominant traits.
There is also some evidence of a recessive inheritance, which means that RLS cases can be transmitted by the less dominant, or processes, gene.
Primary RLS can also show a dopaminergic deficiency, which could result from a malfunction in the brain stem.
Secondary RLS Some teachers of secondary RLS are referred to as risk factors for RLS, or disorders that occur in conjunction with RLS.
Some examples include periodic limb movements (or PLM), early-onset Parkinson's disease, and end-stage renal disease (ESRD).
RLS can be induced by certain drugs, which include all drugs that block the dopamine receptor.
The use of alcohol and caffeine can also trigger Restless Leg Syndrome.
Another trigger could be that of a physical trauma.
There is no formal research that supports this conclusion, but anecdotal evidence is relatively strong.
And people that suffer from this disease often have an operation or accident to the body or brain, which seems to trigger the disease also.
Still others report that RLS worsens after an accident.
Other triggers that are guilty of worsening pre-existing mild RLS include spinal surgery and arthritis of the lumbar region.