Balancing Paediatric Anaesthesia
Balancing Paediatric Anaesthesia
A recent publication has analysed the MAC fractions in children more closely and found the MAC-awake fraction to be lower in children aged 5-8 and 8-12 years old than in adults, which is consistent with the animal data described earlier. However, the margins are narrower than demonstrated in animals (Davidson AJ, Wong A, Knottenbelt G, et al., MAC-awake of sevoflurane in children. Paediatr Anaesth 2008; 18: 702-7).
Note Added in Proof
A recent publication has analysed the MAC fractions in children more closely and found the MAC-awake fraction to be lower in children aged 5-8 and 8-12 years old than in adults, which is consistent with the animal data described earlier. However, the margins are narrower than demonstrated in animals (Davidson AJ, Wong A, Knottenbelt G, et al., MAC-awake of sevoflurane in children. Paediatr Anaesth 2008; 18: 702-7).