Guillain-Barre Syndrome
Guillain-Barre Syndrome
About two-thirds of patients with GBS experience cardiovascular complications and need to be managed appropriately. These changes, attributable to autonomic neuropathy, include heart rhythm abnormalities, blood pressure variability (both hypo- and hypertension), myocardial involvement, acute coronary syndromes, and electrocardiographic changes.
Patients with severe disease should be monitored for cardiac arrhythmia. Nonambulant adult patients are at a risk of venous thromboembolism, usually occurring between 1 to 10 weeks following the onset of symptoms. Subcutaneous low-molecular-weight heparin (LMWH) and graduated compression stockings may be initiated as prophylactic therapy against deep venous thrombosis.
Cardiovascular Complications
About two-thirds of patients with GBS experience cardiovascular complications and need to be managed appropriately. These changes, attributable to autonomic neuropathy, include heart rhythm abnormalities, blood pressure variability (both hypo- and hypertension), myocardial involvement, acute coronary syndromes, and electrocardiographic changes.
Patients with severe disease should be monitored for cardiac arrhythmia. Nonambulant adult patients are at a risk of venous thromboembolism, usually occurring between 1 to 10 weeks following the onset of symptoms. Subcutaneous low-molecular-weight heparin (LMWH) and graduated compression stockings may be initiated as prophylactic therapy against deep venous thrombosis.